15 Delicious Diabetic Beef Casserole Recipes for Any Night

Maintaining a healthy diet while enjoying comfort food is possible with diabetic-friendly casseroles.

These 15 diabetic beef casserole recipes are nutritious, satisfying, and perfect for dinner.

Packed with lean beef, vegetables, and flavorful seasonings, each casserole is designed to be low in carbs and sugar.

From classic baked dishes to creative twists with fresh herbs and wholesome ingredients, there’s a recipe for every taste.

Discover how simple, healthy ingredients can transform your meals into hearty, diabetes-friendly dinners that the whole family will love.

15 Delicious Diabetic Beef Casserole Recipes for Any Night

These 15 diabetic beef casserole recipes prove that healthy eating doesn’t mean sacrificing flavor.

Each dish is hearty, satisfying, and carefully crafted to be low in sugar and carbs.

Perfect for weeknight dinners, meal prepping, or family meals, these casseroles make healthy eating easy and delicious.

From classic favorites to innovative creations, there’s a casserole for every taste and occasion.

Try one today and enjoy a comforting, nutritious, and diabetes-friendly dinner that nourishes your body while delighting your taste buds.

Low-Carb Beef and Vegetable Casserole

Low-Carb Beef and Vegetable Casserole is hearty, nutritious, and diabetes-friendly.

Tender ground beef is combined with a medley of low-carb vegetables and savory herbs.

This casserole is satisfying while keeping blood sugar levels stable.

Ingredients:

• 1 lb lean ground beef
• 1 cup broccoli florets
• 1 cup cauliflower florets
• 1 medium zucchini, diced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup unsweetened tomato sauce
• ½ cup low-fat shredded cheese
• 1 tsp dried oregano
• 1 tsp dried basil
• Salt and pepper to taste

Instructions:

• Preheat oven to 375°F (190°C).
• In a skillet, cook ground beef over medium heat until browned; drain excess fat.
• Add onion and garlic; sauté until softened.
• Stir in broccoli, cauliflower, and zucchini; cook 5 minutes.
• Add tomato sauce, oregano, basil, salt, and pepper; simmer 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle shredded cheese evenly on top.
• Bake 20–25 minutes until cheese is melted and bubbly.
• Cool slightly before serving.

This casserole is hearty, flavorful, and wholesome.

Low-carb vegetables balance nutrition and support blood sugar management.

Perfect for a family dinner or meal prep.

A delicious, diabetes-friendly, and satisfying beef casserole.

Cheesy Spinach Beef Casserole

Cheesy Spinach Beef Casserole is rich, savory, and diabetes-conscious.

Lean ground beef is layered with fresh spinach and a light cheese topping for flavor.

This dish is low in carbs and high in protein.

Ingredients:

• 1 lb lean ground beef
• 3 cups fresh spinach, chopped
• 1 small onion, diced
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ cup shredded mozzarella cheese
• 1 tsp paprika
• ½ tsp black pepper
• ½ tsp salt

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Add onion and garlic; sauté until fragrant.
• Stir in chopped spinach and tomatoes; cook until spinach wilts.
• Season with paprika, salt, and pepper.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle mozzarella evenly on top.
• Bake 20 minutes until cheese is melted and slightly golden.
• Allow to cool slightly before serving.

This casserole is savory, cheesy, and satisfying.

Spinach adds fiber and nutrients while keeping carbs low.

Perfect for a healthy dinner option.

A protein-rich, flavorful, and diabetes-friendly beef casserole.

Mushroom and Beef Casserole

Mushroom and Beef Casserole is earthy, comforting, and low in carbohydrates.

Tender mushrooms combine with lean ground beef to create a rich and filling meal.

Ideal for managing blood sugar while enjoying a hearty dish.

Ingredients:

• 1 lb lean ground beef
• 2 cups mushrooms, sliced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ cup low-fat sour cream
• 1 tsp thyme
• ½ tsp black pepper
• ½ tsp salt
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet and drain excess fat.
• Sauté onion, garlic, and mushrooms until softened.
• Add diced tomatoes, thyme, salt, and pepper; simmer 5 minutes.
• Stir in sour cream until well combined.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and edges bubble.
• Let cool slightly before serving.

This casserole is earthy, creamy, and satisfying.

Mushrooms add texture and nutrients without adding sugar.

Perfect for a cozy, diabetes-friendly dinner.

A wholesome, protein-rich, and low-carb beef casserole.

Zucchini Beef Casserole

Zucchini Beef Casserole is light, flavorful, and diabetes-friendly.

Tender ground beef pairs with fresh zucchini and aromatic spices.

This low-carb dish is perfect for a family dinner or meal prep.

Ingredients:

• 1 lb lean ground beef
• 2 medium zucchinis, sliced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp black pepper
• ½ tsp salt
• 1 tsp Italian seasoning
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until fragrant.
• Add zucchini, tomatoes, Italian seasoning, salt, and pepper; cook 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and the casserole is bubbly.
• Allow to cool slightly before serving.

This casserole is flavorful, tender, and satisfying.

Zucchini adds fiber, keeping the meal light and nutritious.

Perfect for a diabetes-conscious dinner.

A low-carb, protein-rich, and delicious beef casserole.

Cauliflower and Beef Casserole

Cauliflower and Beef Casserole is creamy, hearty, and diabetic-friendly.

Low-carb cauliflower replaces starchy vegetables while providing a soft texture.

Lean beef and cheese make the dish rich yet suitable for blood sugar management.

Ingredients:

• 1 lb lean ground beef
• 3 cups cauliflower florets, steamed
• 1 small onion, chopped
• 2 cloves garlic, minced
• ½ cup unsweetened tomato sauce
• ½ cup low-fat shredded cheese
• 1 tsp dried oregano
• ½ tsp black pepper
• ½ tsp salt

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until softened.
• Stir in steamed cauliflower, tomato sauce, oregano, salt, and pepper.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle shredded cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is creamy, hearty, and satisfying.

Cauliflower keeps carbs low while adding nutrients and fiber.

Perfect for a diabetes-friendly, comforting dinner.

A protein-rich, flavorful, and low-carb beef casserole

Bell Pepper and Beef Casserole

Bell Pepper and Beef Casserole is colorful, hearty, and diabetes-friendly.

Lean ground beef is combined with sweet bell peppers, onions, and spices for a filling low-carb meal.

Perfect for managing blood sugar without sacrificing flavor.

Ingredients:

• 1 lb lean ground beef
• 2 large bell peppers, diced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp black pepper
• ½ tsp salt
• 1 tsp smoked paprika
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet and drain excess fat.
• Sauté onion and garlic until fragrant.
• Add diced bell peppers, tomatoes, smoked paprika, salt, and pepper; cook 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is colorful, savory, and filling.

Bell peppers add fiber, vitamins, and low-carb nutrition.

Perfect for a diabetes-conscious, balanced dinner.

A hearty, flavorful, and wholesome beef casserole.

Eggplant and Beef Casserole

Eggplant and Beef Casserole is rich, savory, and low in carbs.

Tender eggplant layers with ground beef and tomatoes create a satisfying meal suitable for diabetics.

Ideal for a comforting dinner that won’t spike blood sugar.

Ingredients:

• 1 lb lean ground beef
• 1 medium eggplant, diced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp dried oregano
• ½ tsp black pepper
• ½ tsp salt
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until softened.
• Add diced eggplant, tomatoes, oregano, salt, and pepper; cook 5–7 minutes until eggplant softens.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 25 minutes until cheese melts and casserole is bubbling.
• Let cool slightly before serving.

This casserole is hearty, creamy, and satisfying.

Eggplant adds fiber and keeps the dish low in carbohydrates.

Perfect for a nutritious, diabetes-friendly dinner.

A flavorful, protein-rich, and comforting beef casserole.

Cabbage and Beef Casserole

Cabbage and Beef Casserole is light, savory, and low-carb.

Tender cabbage mixes with lean ground beef for a filling, diabetes-conscious meal.

Ideal for a family dinner or meal prep.

Ingredients:

• 1 lb lean ground beef
• 3 cups shredded cabbage
• 1 small onion, chopped
• 2 cloves garlic, minced
• ½ cup diced tomatoes, no sugar added
• ½ tsp salt
• ½ tsp black pepper
• 1 tsp paprika
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until softened.
• Add shredded cabbage, tomatoes, paprika, salt, and pepper; cook 5 minutes until cabbage softens.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is light, savory, and satisfying.

Cabbage adds fiber and helps keep carbs low.

Perfect for a healthy, diabetes-friendly dinner.

A protein-rich, flavorful, and nutritious beef casserole.

Zucchini and Beef Bake

Zucchini and Beef Bake is tender, savory, and low in carbohydrates.

Ground beef combines with sliced zucchini and herbs to create a diabetes-conscious meal.

Ideal for a hearty and satisfying dinner.

Ingredients:

• 1 lb lean ground beef
• 2 medium zucchinis, sliced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp dried basil
• ½ tsp salt
• ½ tsp black pepper
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until fragrant.
• Add zucchini, tomatoes, basil, salt, and pepper; cook 5 minutes until zucchini softens.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is tender, savory, and wholesome.

Zucchini adds nutrients and keeps the meal low in carbs.

Perfect for a diabetes-conscious dinner or meal prep.

A flavorful, protein-rich, and satisfying beef casserole.

Cauliflower and Beef Bake

Cauliflower and Beef Bake is creamy, nutritious, and diabetic-friendly.

Cauliflower adds bulk and fiber while keeping carbohydrates low.

Ground beef and cheese provide flavor and protein for a hearty dinner.

Ingredients:

• 1 lb lean ground beef
• 3 cups cauliflower florets, steamed
• 1 small onion, chopped
• 2 cloves garlic, minced
• ½ cup unsweetened tomato sauce
• ½ tsp salt
• ½ tsp black pepper
• 1 tsp dried oregano
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until softened.
• Stir in steamed cauliflower, tomato sauce, oregano, salt, and pepper.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Let cool slightly before serving.

This casserole is creamy, hearty, and filling.

Cauliflower keeps carbs low while adding fiber and nutrients.

Perfect for a diabetes-friendly, comforting dinner.

A protein-rich, savory, and satisfying beef casserole

Bell Pepper, Tomato, and Beef Casserole

Bell Pepper, Tomato, and Beef Casserole is colorful, hearty, and low-carb.

Sweet bell peppers and juicy tomatoes mix with lean ground beef for a diabetes-friendly meal.

Ideal for a filling, nutritious dinner without spiking blood sugar.

Ingredients:

• 1 lb lean ground beef
• 2 large bell peppers, diced
• 1 cup cherry tomatoes, halved
• 1 small onion, chopped
• 2 cloves garlic, minced
• ½ tsp salt
• ½ tsp black pepper
• 1 tsp Italian seasoning
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until fragrant.
• Add bell peppers, cherry tomatoes, Italian seasoning, salt, and pepper; cook 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is colorful, savory, and satisfying.

Bell peppers and tomatoes add fiber, vitamins, and antioxidants.

Perfect for a diabetes-conscious dinner.

A hearty, flavorful, and nutritious beef casserole.

Spinach and Beef Casserole

Spinach and Beef Casserole is rich, flavorful, and low-carb.

Fresh spinach combines with ground beef and spices for a wholesome, diabetes-friendly meal.

Perfect for dinner or meal prep with balanced nutrition.

Ingredients:

• 1 lb lean ground beef
• 3 cups fresh spinach, chopped
• 1 small onion, diced
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp salt
• ½ tsp black pepper
• ½ tsp paprika
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until fragrant.
• Add chopped spinach, diced tomatoes, salt, pepper, and paprika; cook 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Let cool slightly before serving.

This casserole is savory, rich, and filling.

Spinach adds fiber, vitamins, and minerals while keeping carbs low.

Perfect for a healthy, diabetes-conscious dinner.

A protein-rich, flavorful, and wholesome beef casserole.

Mushroom, Zucchini, and Beef Casserole

Mushroom, Zucchini, and Beef Casserole is hearty, nutritious, and diabetes-friendly.

Tender mushrooms and zucchini mix with lean beef to create a balanced, low-carb meal.

Ideal for a cozy family dinner.

Ingredients:

• 1 lb lean ground beef
• 2 cups mushrooms, sliced
• 1 medium zucchini, sliced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp salt
• ½ tsp black pepper
• ½ tsp thyme
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion, garlic, mushrooms, and zucchini until softened.
• Add diced tomatoes, thyme, salt, and pepper; simmer 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is earthy, savory, and satisfying.

Mushrooms and zucchini add fiber and nutrients while keeping carbs low.

Perfect for a balanced, diabetes-friendly dinner.

A protein-rich, wholesome, and flavorful beef casserole.

Cauliflower, Tomato, and Beef Casserole

Cauliflower, Tomato, and Beef Casserole is creamy, hearty, and low-carb.

Steamed cauliflower replaces starchy vegetables while lean beef adds protein.

Perfect for managing blood sugar while enjoying a comforting meal.

Ingredients:

• 1 lb lean ground beef
• 3 cups cauliflower florets, steamed
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp oregano
• ½ tsp salt
• ½ tsp black pepper
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until softened.
• Add steamed cauliflower, diced tomatoes, oregano, salt, and pepper; cook 5 minutes.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is creamy, hearty, and flavorful.

Cauliflower adds fiber and nutrients while keeping the dish low-carb.

Perfect for a diabetes-friendly, satisfying dinner.

A protein-rich, wholesome, and comforting beef casserole.

Eggplant, Bell Pepper, and Beef Casserole

Eggplant, Bell Pepper, and Beef Casserole is savory, colorful, and low-carb.

Tender eggplant and sweet bell peppers mix with lean beef for a diabetes-conscious meal.

Ideal for a hearty and nutritious dinner.

Ingredients:

• 1 lb lean ground beef
• 1 medium eggplant, diced
• 1 large bell pepper, diced
• 1 small onion, chopped
• 2 cloves garlic, minced
• 1 cup diced tomatoes, no sugar added
• ½ tsp salt
• ½ tsp black pepper
• ½ tsp Italian seasoning
• ½ cup shredded low-fat cheese

Instructions:

• Preheat oven to 375°F (190°C).
• Brown ground beef in a skillet; drain excess fat.
• Sauté onion and garlic until fragrant.
• Add eggplant, bell pepper, diced tomatoes, Italian seasoning, salt, and pepper; cook 5–7 minutes until vegetables soften.
• Transfer mixture to a greased 9×13-inch baking dish.
• Sprinkle cheese evenly on top.
• Bake 20–25 minutes until cheese melts and casserole is bubbly.
• Cool slightly before serving.

This casserole is savory, colorful, and satisfying.

Eggplant and bell peppers provide fiber and essential nutrients.

Perfect for a diabetes-friendly, balanced dinner.

A protein-rich, flavorful, and low-carb beef casserole.